Pierre Cherel & Emilie Panafieu

Imagine has an animal facility, where animal welfare is a priority. The use of animal models only take place if no other solution is possible to answer the question.

Among the models available are Drosophila, zebrafish and murine models.

In 2015, the transgenesis platform opened at the Animal facility. Its main mission is the generation of murine strains using the CRISPR/Cas9 technology.

This facility is organized on two different sites :

• LEAT Broussais Facility
• LEAT Imagine Facility

The platform is composed of different zones and offers several services :

• Housing and breading mice in IVC (Individual Ventilated Cages) or isolators
• Maintenance of mouse strains and animal production for experiments according to established protocols
• Housing and maintenance of zebrafish lines
• Technical support
• Sperm Cryopreservation
• Transgenesis